| abstract |
The present invention relates to a compound represented by the following formula (1), a method for preparing the same, and a pharmaceutical composition comprising the same. Specifically, the compound of the present invention relates to SH2 (src homology region 2) of T lymphocyte cell kinase (lck). As a immunosuppressive agent by inhibiting the activity of T lymphocytes through the) domain, it may be useful for the treatment, diagnosis or prevention of rejection, autoimmune diseases, inflammatory diseases, etc., which occur when transplantation of organs or tissues.n n n n n n n n n n (The above R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , R 8 , R 9 , R 10 , X 1 , X 2 , X 3 , Y 1 , Y 2 , B and * Is as described in the specification.) |