http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100510624-B1
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-505 |
classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P13-12 |
filingDate | 2000-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2005-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2005-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-100510624-B1 |
titleOfInvention | Erythropoietin conjugates with polyethylenglycol |
abstract | Erythropoietin glycoprotein conjugates are disclosed that have one or more free amino groups and have in vivo biological activity that allows bone marrow cells to increase the production of reticulocytes and erythrocytes and human erythropoietin and one to six Erythropoietin glycoproteins selected from the group consisting of analogues of human erythropoietin having a primary structure of human erythropoietin modified by addition of a glycosylation site or rearrangement of one or more glycosylation sites; The glycoprotein is covalently linked to one to three C 1-6 -alkoxy poly (ethylene glycol) groups, each poly (ethylene glycol) group covalently attached to the glycoprotein by a linker of formula (I) C (O) of the linker forms an amide bond with one of the amino groups), the average molecular weight of each poly (ethylene glycol) residue is 24 to 35 kDa and the molecular weight of the conjugate is 51 to 175 kDa:n n n Formula In n n -C (O) -X-S-Y-n n n Wheren n n X and Y are as defined in the specification and claims. |
priorityDate | 1999-07-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 299.