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publicationDate 2005-04-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber KR-100482379-B1
titleOfInvention Novel microorganism capable of metabolizing isoflavone
abstract Provided is a microorganism capable of metabolizing isoflavones. The isoflavone metabolites has improved estrogen effect. Therefore, isoflavone metabolites are useful for prevention and treatment of osteoporosis, and are useful as antioxidant, anticancer and antimutation agent. The microorganism capable of metabolizing isoflavones is SNU-NiuO16(KCCM-10491), wherein the microorganism SNU-NiuO16(KCCM-10491) is isolated from the stomach of cow; the isoflavones are daidzein and genistein; and the isoflavone metabolites are dihydrodaidzein and dihydrogenistein. The method for producing the isoflavone metabolites comprises inoculating the microorganism SNU-NiuO16(KCCM-10491) into BHI medium and culturing the microorganism under anaerobic condition consisting of 5-10% CO2, 5-15% H2 and 75-90% N2; and the initial pH of the medium is 6.0-8.0 and final concentration of isoflavone in the medium is 400-8900 microM.
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