http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100479837-B1
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12R2001-29 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P7-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P17-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-205 |
classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-29 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-31 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P17-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P7-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P7-62 |
filingDate | 2000-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2005-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2005-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-100479837-B1 |
titleOfInvention | A microbial process for the pravastatin by micromonospora strain |
abstract | The present invention provides a product of formula (I) which is formed during a biotransformation and culture of a strain capable of 6β-hydroxylation of a compound of formula (II) by aerobic fermentation.n n n Formula In n n n n n n n Compound of Formula (II) by Separation and Purificationn n n Formula IIn n n n n n n n And a novel process for microbially preparing a compound of formula (I). The latter method of separation and purification involves the following steps:n n n a) Cultivating micromonospora strains capable of 6β-hydroxylation of compounds of formula II (where R is as described above) at 25-32 ° C. on a common medium containing an available carbon source, nitrogen source and mineral salts next ;n n n b) adding a substrate for transformation into the developed culture;n n n c) hydroxylating the substrate until the end of bioconversion;n n n d) Isolate the compound of formula I from the culture broth and purify it as necessary. |
priorityDate | 1999-07-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 395.