http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100469661-B1
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2430-40 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01N1-0221 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0625 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N1-02 |
filingDate | 2000-03-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2005-02-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2005-02-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-100469661-B1 |
titleOfInvention | Acellular Dermal Matrix for Transplantation and Process for Preparing the Same |
abstract | The present invention isolates the dermal layer from the skin tissue extracted from the donor, by removing the cells from the separated dermal layer, to prepare a cell-free dermal layer for transplantation in which the immune rejection-inducing substance is removed, and the transplanted radish prepared by the electrical method It relates to the cell dermal layer. Method for producing a cell-free dermal layer for transplantation of the present invention is to extract the skin tissue including the epidermal layer and the dermal layer from the donor, comprising an antibiotic, an antimicrobial agent and a protease inhibitor at 2 to 10 ℃, osmotic pressure of 260 to 320m0sm / kg Immersing in a solution to maintain; Washing the submerged skin tissue, treating the neutral proteolytic enzyme or ionic solution to remove the epidermal layer, and then obtaining a dermal layer; And removing the cells using the surfactant treatment, the ultrasonic treatment, or a combination thereof to the obtained dermal layer. According to the present invention, since the causative agent causing the immune response is removed, the tissue is not released due to the immune rejection reaction after transplantation, and thus it may be widely used for the development of the skin for transplantation. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023136538-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018048047-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11109955-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101710615-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023003430-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023003431-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-102586360-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-102366303-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101330646-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101029887-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20230108849-A |
priorityDate | 2000-03-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 125.