http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100461569-B1

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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-04
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-04
filingDate 2002-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2004-12-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2004-12-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber KR-100461569-B1
titleOfInvention Process for producing optically pure 3-hydroxy-pyrrolidine
abstract The present invention relates to a method for preparing optically pure 3-hydroxy-pyrrolidine, and more particularly, to react with ammonia and an aldehyde compound using 3,4-epoxy-1-butanol having optical activity as a starting material. After preparing the 4-protected imino-butane-1,3-diol, the hydroxy group at the C-1 position is selectively activated, or subsequently treated with an acid to convert the imino group into an amine group, and then in the presence of a base. By carrying out an intramolecular cyclization reaction, it relates to a novel process for producing 3-hydroxy-pyrrolidine represented by the following formula (1) economically and simply in high yield optically.n n n n n n n n n n In Chemical Formula 1, * represents a compound (S) or (R) having optical activity.
priorityDate 2002-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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