| abstract |
The present invention describes compounds of formula (I)n n n <Formula I>n n n n n n n n Wherein R 1 is halogen, hydroxyl, C 1-8 alkyloxy or C 1-12 acyloxy, R 2 is halogen or hydrogen, or R 1 and R 2 together form a double bond, Z Is optionally substituted C 1-8 alkylthio, optionally substituted arylthio, C 1-8 alkyloxy, halogen, cyano, mercapto, thiocyanato and optionally esterified (CH 2 ) 0-1 CO 2 Selected from H, Y is hydrogen or methyl and the dashed lines at positions 1 and 2 or 5 and 6 possibly represent a second bond. Also described are addition salts, methods of preparation and intermediates thereof, and pharmaceutical compositions containing these materials. |