http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100449652-B1
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-79 |
filingDate | 2001-07-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2004-09-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2004-09-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-100449652-B1 |
titleOfInvention | Method for gene therapy of cancer using co-transfection with anti-apoptotic genes and anti-tumor suicide genes |
abstract | The present invention relates to a method of increasing apoptosis by using simultaneous expression of a suicide gene and an anti-apoptosis gene, and a gene therapy use of the cancer using the same. Apoptosis of the tumor cell line by antagonism between the suicide gene HSV-TK (Herpes simplex virus-thymidine kinase) and the anti-apoptotic gene bcl-xL or bfl-1 simultaneously in the tumor cell line. ) Is used to treat tumors by destroying tumors. The method of simultaneously expressing the suicide gene and the anti-apoptotic gene of the present invention can be used for the removal of tumor cells, and can be effectively used for the treatment of cancer because it is effective even for cancers that cannot be treated by chemotherapy and can be treated in a short time. . |
priorityDate | 2001-07-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 189.