http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100439069-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J9-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J9-00 |
| filingDate | 2002-04-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2004-07-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2004-07-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-100439069-B1 |
| titleOfInvention | Ultra-fine needle crystaline Ursodeoxycholic acid and process for preparation thereof |
| abstract | The present invention provides a new method for crystallization of Ursodeoxycholic acid ("UDCA") represented by the following general formula (1). In this method, UDCA is dissolved in methyl alcohol or ethyl alcohol, and then a mixed solvent of distilled water mixed with acetonitrile or acetone is added thereto, followed by stirring. Then, an excessive amount of distilled water is temporarily added under ice-cooling until an emulsion is formed. It is characterized by forming crystalline ultrafine particles of.n n n According to the present invention, crystallization takes place at a time without time consuming, and afterwards, it is possible to obtain a high-purity target compound without grinding after drying, and more importantly, the in-vitro dissolution rate is increased than in the conventional method. Has the advantage. |
| priorityDate | 2002-04-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 30.