http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100436554-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6834 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-68 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-566 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N37-00 |
| filingDate | 2001-04-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2004-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2004-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-100436554-B1 |
| titleOfInvention | A Method for Improving a Sensitivity of Sensing Device in the Detection of a Hybridized Nucleic Acid |
| abstract | The present invention provides a method of increasing hybridization detection sensitivity of nucleic acid immobilized on a substrate of a sensor device for genetic analysis by removing a nonhybridized nucleic acid probe using a nucleic acid hydrolase. The method of the present invention reduces or eliminates background signals generated by single-stranded nucleic acid probes that remain unhybridized with the target nucleic acid or signals due to nonspecific binding between the target nucleic acid and the probe, thereby reducing the sensitivity and accuracy of hybridization detection of the nucleic acid. It can increase. In addition, the method of the present invention can minimize the loss of hybridized nucleic acid, which occurs in existing methods of reducing background signal by washing. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008103015-A1 |
| priorityDate | 2001-04-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 38.