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filingDate 1996-02-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2005-05-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_09c72dd8202da3fbb749f1b860180ee0
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publicationDate 2005-05-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber KR-100434023-B1
titleOfInvention Animal cell line expressing glycoprotein of varicella-zoster virus
abstract The present invention relates to a transformed animal cell line which continuously and stably expresses the surface antigen protein of Varicella-Zoster Virus (VZV), the hydrophobic region at the carboxy terminus from the surface antigen glycoprotein gpII of chickenpox virus (VZV). The gpIIs protein of VZV prepared by culturing a CHO cell line transformed with a bicistronic expression vector in which the gene encoding the protein gpIIs and the selection gene were removed by a single promoter can be used as a vaccine highly resistant to VZV. have.
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