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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H17-04
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H17-04
filingDate 1996-12-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2004-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2004-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber KR-100414706-B1
titleOfInvention Process for producing etoposide compounds
abstract The ratio of the protected 4'-demethyl-4-epipodophyllotoxin and the protected glucose derivative in an amount of 0.1 to 7 times by volume relative to 1 part by weight of the protected 4'-demethyl-4-epipodophyllotoxin The reaction is carried out in a (non) halogen-type organic solvent to prepare an etoposide derivative of the formula (3) in which the terminal group is protected, and then these protecting groups are removed as necessary.n n n n n n n n (Wherein R 1 and R 2 are each a protecting group of hydroxy)n n n By using a non-halogen type organic solvent in place of the harmful halogen solvent, it is possible to minimize the generation of unnecessary by-products, so that etoposide can be produced in high purity and high yield.
priorityDate 1995-12-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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