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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-495
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D241-02
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filingDate 1995-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2004-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2004-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber KR-100412167-B1
titleOfInvention Piperazine-2,5-dione derivatives as modulators for multidrug resistance
abstract Piperazinedione of formula (I) and its pharmaceutically acceptable salts have activity as modulators of multiple drug resistance.n n n [Formula I]n n n n n n n n In the above formula,n n n R 1 is hydrogen; Formula -COR 3- (NH) t -COR 3 wherein t is 0 or 1 and R 3 is selected from (i) Formula A, (ii) Formula B, (iii) Formula C and (iv) Formula F do]; Is selected from the group of formula D and the group of formula E;n n n R 2 is hydrogen or a group of formula -COR 3 as defined above,n n n Provided that one of R 1 and R 2 is hydrogen and the other is not hydrogen,n n n [Formula A]n n n n n n n n [Formula B]n n n n n n n n [Formula C]n n n n n n n n Formula F]n n n n n n n n In Chemical Formulas A, B, C and F,n n n v is 0 when t is 1 and 1 when t is 0;n n n n is 0, 1, 2 or 3;n n n at least one of n and m is a number other than 0;n n n p is 1 or 2,n n n Z is C 2 -C 6 alkenyl or a phenyl group unsubstituted or substituted by C 1 -C 6 alkoxy,n n n R 9 is C 1 -C 6 alkyl, pyrimidinyl or phenyl unsubstituted or substituted by C 1 -C 6 alkoxy.
priorityDate 1994-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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