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filingDate 2000-10-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2003-10-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2003-10-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber KR-100402049-B1
titleOfInvention Method for preparing chiral ester
abstract The present invention selectively selects a ketone, a ruthenium complex of Formulas 1 to 3 which promotes a reaction of reducing the ketone to racemic alcohol and a racemization reaction of the racemic alcohol, and an enantiomer of one of the racemic alcohols. It provides a lipase to be acylated, a hydride donor for supplying a hydride to the ruthenium complex, and an acyl donor for supplying an acyl group to the lipase, and a method for producing a chiral ester. According to the present invention, chiral esters having excellent optical purity characteristics can be obtained in a high synthetic yield through a one-step reaction from ketones.n n n n n n n n n n In the above formula, Y 1 , Y 2 , Y 3 , Y 4 , Y 5 , Y 6 , Y 7 , Y 8 , Y 9 , Y 10 , Y 11 , Y 12 represent a single bond irrespective of each other, Hydrogen or an alkyl group having 1 to 5 carbon atoms, X is Br, Cl or I,n n n n n n n n n n In the above formula, Y 1 , Y 2 , Y 3 , Y 4 , Y 5 , Y 6 , Y 7 , Y 8 , Y 9 , Y 10 , Y 11 , Y 12 represent a single bond irrespective of each other, Hydrogen or an alkyl group having 1 to 5 carbon atoms, and X is Br, Cl or I.
priorityDate 1999-10-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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