http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100395985-B1

Outgoing Links

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filingDate 1997-12-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2004-02-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2004-02-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber KR-100395985-B1
titleOfInvention Vinyl pyrrolidinone cephalosporins with basic substituents
abstract The present invention relates to cephalosporin derivatives of formula (1), easily hydrolyzable esters thereof and pharmaceutically acceptable salts of the compounds, and hydrates of compounds of formula (1), esters and salts thereof:n n n n n n n n n n Wheren n n X is CH or N;n n n R 1 is hydrogen or cyclopentyl;n n n R 2 is a group of the following general formula,n n n n n n n n R 3 is hydrogen, an alkali metal ion or a tertiary ammonium group;n n n R 4 is hydrogen, amino protecting group, pyrrolidin-2-ylmethyl, azetidin-3-ylmethyl, iminomethyl, 1-carbamimidoyl;n n n R 5 is hydrogen, dialkylcarbamoyl, ω-hydroxyalkyl, ω-aminoalkyl, pyridinium-1-ylmethyl, 1-hydroxy-3-aminomethyl-propyl or (hydroxy)-(pyrrolidine -2-yl) methyl;n n n R 6 is hydrogen, trifluoromethyl or hydroxy;n n n R 7 is alkyl, ω-hydroxy-alkyl, cycloalkyl, 3-pyrrolidinyl, 3-azetidinyl, iminomethyl or 1-carbamididoyl.n n n The invention further provides methods for the preparation of compounds of formula 1, in particular their use as pharmaceutically active substances for the treatment and prevention of infectious diseases, and agents for the treatment and prevention of infectious diseases containing compounds of formula 1 It is about.
priorityDate 1996-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 35.