| abstract |
The present invention relates to a pharmaceutical composition for the prevention and treatment of sexual dysfunction and vascular diseases containing Icarin as an active ingredient. Icarin has a strong relaxation effect in the corpus cavernosum, which not only improves sexual function, but also relaxes the vascular smooth muscle and arterial vessels, and its mechanism of action is the production of nitric oxide (NO) and cGMP in the corpus cavernosum and arteriovascular smooth muscle. Increasing activation leads to smooth muscle relaxation, promotes erection and has a therapeutic effect on vascular diseases. In addition, Icarin has little side effects when treating sexual dysfunction and can be used safely and effectively in patients with diabetes, hypertension and heart disease. Therefore, the pharmaceutical composition of the present invention containing ikirin can be used safely and effectively as a medicament for the prevention and treatment of sexual dysfunction and vascular diseases. |