Predicate |
Object |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D493-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F7-1804 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F7-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D305-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-335 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D263-04 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D263-04 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-337 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-335 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D305-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D263-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D493-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F7-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
filingDate |
1996-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2003-10-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate |
2003-10-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
KR-100388878-B1 |
titleOfInvention |
10-Deacetyl Bacatin III and 10-Deacetyl-14β-Hydroxybacatin III Derivatives, Methods of Making Them, and Pharmaceutical Compositions Containing Them |
abstract |
The present invention relates to novel derivatives of 10-deacetylbacatin III and 10-deacetyl-14β-hydroxybacatin III having cytotoxic and anticancer activity.n n n These compounds are prepared by selectively oxidizing hydroxyls to have a keto function at position 10, starting with natural taxanes or their homologues, and then esterifying with several substituted isocerine chains at position 13 as needed.n n n The product of the present invention may be administered orally or by injection in a suitable formulation. |
priorityDate |
1995-03-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |