| Predicate |
Object |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-322
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-346
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-345
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-318
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-315
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-341
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-321 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1135
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6876
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H21-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7125
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate |
1998-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2002-10-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate |
2002-10-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
KR-100354610-B1 |
| titleOfInvention |
Antisense Inhibition of ras Gene with Chimeric and Alternating Oligonucleotides |
| abstract |
The present invention provides compositions and methods for controlling ras gene expression in humans with normal and activated forms. The present invention provides an oligonucleotide having a methylene (methyllimino) linking group which alternately binds to a phosphorothioate linking group or a phosphodiester linking group. The present invention also provides an oligonucleotide having a first region having a methylene (methyllimino) linking group that crosslinks a phosphorothioate linking group or a phosphodiester linking group and a second region having a phosphorothioate linking group. Such oligonucleotides are used in diagnostics as well as for research purposes, including methods for diagnosing, detecting, and treating diseases resulting from the activation of human H-ras genes. |
| priorityDate |
1997-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |