http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100343394-B1
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C69-757 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-757 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-00 |
filingDate | 1999-04-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2002-07-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2002-07-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-100343394-B1 |
titleOfInvention | Novel aklavinone derivative and preparation method thereof |
abstract | The present invention relates to a novel aclabinone derivative and a method for producing using a microorganism, and a transformant used for the preparation of the compound, and more particularly, to aclabinone C-11 hydroxy isolated from a strain of Streptomyces spp. Biosynthetic mutants were transformed with a vector containing a silase gene, followed by culturing the transformant to prepare 2,11-dihydroxyaclabinone, a novel aclabinone derivative of Formula 1 below. It can be used as a precursor for preparing new anthracycline antibiotics, and the anthracycline antibiotics obtained by the bioconversion method can be used as an effective antibiotic with low side effects due to low cytotoxicity. |
priorityDate | 1999-04-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 81.