http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100332219-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N27-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N27-327 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N27-49 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01D71-76 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-48 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N27-31 |
| filingDate | 1999-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2002-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2002-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-100332219-B1 |
| titleOfInvention | Reaction membrane for bio senser and manufacturing method corresponding the same |
| abstract | 1. TECHNICAL FIELD OF THE INVENTIONn n n Biosensing membrane and its manufacturing methodn n n 2. Technical problem to be solved by the inventionn n n According to the present invention, a simple and reproducible formation of an inner film having a small but uniform thickness and desired physical properties by using an electrochemical polymer polymerization method and a stable background signal can be obtained in a short time while maintaining high sensitivity by reliably fixing the enzyme. It is an object of the present invention to provide a biosensor-sensitive film and a mass production method thereof.n n n 3. Summary of Solution to Inventionn n n The present invention is directed to an aromatic derivative inner film laminated on a portion of an electrode wrapped with a Teflon envelope and having selective permeability; An enzyme immobilization layer formed on the aromatic derivative inner layer and immobilized on the inside of the polymer formed by a polymerization reaction of aromatic derivative monomers to produce a hydrogen peroxide by causing a chemical reaction with an external analyte; And laminated on the enzyme fixation layer to protect the inner membrane and the enzyme fixation layer, enhance biocompatibility, minimize the influence of external disturbances, and prevent hydrogen peroxide produced by the chemical reaction of the enzyme from diffusing to parts other than the inner membrane. Provided is a sensitized film comprising a polymer outer membrane having a fluorine-substituted carbon chain.n n n In addition, the present invention comprises a first step of impregnating an electrode in an aqueous solution in which a predetermined aromatic derivative, hydrogen chloride and electrolyte are dissolved; A second step of forming an inner layer of an aromatic derivative having a predetermined thickness with an electrochemical polymerization reaction on the surface of the electrode in the aqueous solution, with selective permeability to hydrogen peroxide; A third step of impregnating an electrode having a polymer inner film including the aromatic derivative as a monomer in an aqueous solution in which an enzyme, an aromatic derivative, and an electrolyte are dissolved; A fourth step of forming an enzyme layer on the inner membrane by causing an electrochemical polymerization reaction on the surface of the polymer inner membrane using the aromatic derivative as a monomer in the aqueous solution; It provides a sensitized membrane manufacturing method comprising a fifth step of forming an outer membrane by impregnating and drying an electrode in which an inner layer and an enzyme layer are sequentially stacked in a solution of a dilute aqueous solution in which a polymer having a fluorine-substituted carbon chain is dispersed. .n n n 4. Important uses of the inventionn n n The present invention is to form a film having a thin thickness, uniformity and desired physical properties by manufacturing the sensitized film used in the biosensor by the electrochemical polymer polymerization method. |
| priorityDate | 1999-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 80.