http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100328481-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-496 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N25-08 |
| filingDate | 1999-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2002-03-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2002-03-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-100328481-B1 |
| titleOfInvention | Antifungal composition comprising itraconazole and preparation method thereof |
| abstract | The present invention relates to an antifungal preparation containing itraconazole and a method for preparing the same. More specifically, in the preparation containing amorphous itraconazole, oral antifungal preparations having improved stability by inhibiting drug recrystallization over time. And a method for producing the same. The present invention comprises an itraconazole-containing antifungal agent, characterized in that it comprises an amorphous itraconazole and colloidal silica, light silicic anhydride, heavy silicic anhydride, sodium chloride, potassium aluminosilicate, calcium aluminosilicate, and the like. According to the present invention, it is possible to prevent a decrease in solubility over time by amorphizing the itraconazole, which is poorly absorbed in vivo due to low solubility, and to prevent the drug from being recrystallized over time. Can be. |
| priorityDate | 1999-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 27.