http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100327971-B1
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-56 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-70 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-21 |
filingDate | 1999-04-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2002-03-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2002-03-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-100327971-B1 |
titleOfInvention | Process for Preparing Amino-terminal Methionine Free Recombinant Interferon-alpha |
abstract | The present invention relates to a method for producing a recombinant interferon-α from which the methionine present at the amino terminus is removed from the transformed recombinant E. coli. In the present invention, a method for preparing recombinant interferon-α from which amino terminal methionine is removed is treated with aminopeptidase to partially purified recombinant interferon-α, and purified methionine-removed recombinant interferon-α using cation exchange chromatography. It includes a process to make. According to the present invention, the recombinant interferon-α from which the amino terminal methionine is removed can be produced more reliably and clinically and more securely suitable for a recombinant protein for therapeutic purposes intended for in vivo administration. |
priorityDate | 1999-04-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 41.