http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100309871-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D265-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D215-56 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5383 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D498-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D265-34 |
| filingDate | 1999-02-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2001-10-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2001-10-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-100309871-B1 |
| titleOfInvention | Process for Preparing (-)Pyridobenzoxazine Carboxylic Acid Derivatives |
| abstract | The present invention relates to a novel method for preparing optically active (-) pyridobenzoxazine carboxylic acid derivatives having excellent antibacterial action and pharmaceutically acceptable salts thereof. The optically active (-) pyridobenzoxazine carboxylic acid derivative (I) of the present invention and a pharmaceutically acceptable salt thereof are prepared by the substitution reaction of the compound (V) shown below with a suitable reactive substance in the presence of a base. Compound (III) is obtained by cyclization of compound (IV) in the presence of an organic polar solvent and a base, and then compound (III) is selected with a piperazine derivative substituted in the presence of an organic polar solvent and a base. Compound (II) was formed by a general substitution reaction, and then compound (II) was prepared by hydrolysis and cyclization reaction using a metal hydroxide and an organic solvent. The method of the present invention uses starting materials prepared from inexpensive 4-chloro-5-fluoro-2-halo-3-nitrobenzoic acid derivatives, and the reaction process is simple and economically economical (-) pyridobenz Applicable to mass production of oxazine carboxylic acid derivatives. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100542600-B1 |
| priorityDate | 1999-02-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 72.