http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100292331-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_42e94091a4fc81b8d0237117707cc7ee |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D305-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D409-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D407-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C233-82 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D305-14 |
| filingDate | 1993-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2001-09-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_926e7488e4fbca8621d73d14529b7cc5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_18df591212f639f4cb0db566c78819ae http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_91f4ccd676874699f02c5f91842f6e9d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a4b90cbf86ebafdd873cb70a31c09c26 |
| publicationDate | 2001-09-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-100292331-B1 |
| titleOfInvention | Fluorotaxol |
| abstract | The present invention relates to fluorinated taxols of general formula (I):n n n n n n n n In the above formula,n n n R 1 is -COR z and R z is R0- or R;n n n R g is C 1-6 alkyl, C 2-6 alkenyl, C 2-6 alkynyl, C 3-6 cycloalkyl, or a radical of the formula -WR x , where W is a bond, C 2-6 alkendi Day, or-(CH 2 ) t- , t is 1-6; R x is naphthyl, furyl, thienyl or phenyl, and R x may optionally be substituted with one to three identical or different C 1-6 alkyl, C 1-6 alkoxy, halogen or —CF 3 groups;n n n R 2 is —OCOR, H, 0H, —0R, —OS0 2 R, —OCONR O R, —0COO (CH 2 ) t R, or —OCOOR;n n n R and R 0 are each C 1-6 alkyl, C 2-6 alkenyl, C 3-6 cycloalkyl, C 2-6 alkynyl, or phenyl, optionally 1 to 3 identical or different C 1-6 Substituted with alkyl, C 1-6 alkoxy, halogen or —CF 3 groups.n n n Also provided by the present invention are intermediates useful for pharmaceutical formulations and fluorinated taxols of general formula (I). A method of treating a mammalian tumor using a compound of formula (I) is provided. |
| priorityDate | 1992-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 125.