http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100288890-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9c01da929592a87800d30c608bac9e20 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-496 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-495 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-10 |
| filingDate | 1998-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2001-05-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_49721db4a69bc2544a1c62fe65ef2d7b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_32d7ec35115f2d4c8a5cb9d0c3f3fe0c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_57faf54239da094f2796b6b415f59df5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9a402a12a4746317462bc992107aa4b6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3bda7a90aef1f5646618d3be175c7de8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4d7cb04e889f7757c354855c2e7caa66 |
| publicationDate | 2001-05-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-100288890-B1 |
| titleOfInvention | Itraconazole oral preparation and preparation method thereof |
| abstract | The present invention was prepared by dissolving, dispersing and spray-drying 0.5 to 5.0 parts by weight of pH-dependent and inert water-soluble polymer in one or more solvents selected from methylene chloride, chloroform, ethanol and methanol in 1 part of itraconazole to form a solid dispersion. The present invention relates to an itraconazole oral preparation having improved bioavailability. In other words, in the present invention, in the preparation of oral dosage form of poorly soluble itraconazole in water, the pharmaceutical composition is dispersed and spray-dried using a pH-dependent water-soluble polymer that has a characteristic of rapidly dissolving at a low pH and eluting in a short time. The present invention relates to an itraconazole oral preparation and a method for preparing the same, which greatly improve solubility and elute rapidly regardless of food intake, thereby improving the bioavailability of itraconazole. |
| priorityDate | 1997-12-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 39.