http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100285254-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b42c3a5c8d65a8d12c0d0d4d1741c089 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2531-113 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-689 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-686 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate | 1998-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2001-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1486b80a87d6791043954da7f77d1e83 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d4c97adcec00efae4ab0ef08bd6bfc34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ffaf859b3057bf17c44f297bb038e334 |
| publicationDate | 2001-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-100285254-B1 |
| titleOfInvention | Diagnostic reagent for the detection of mycobacterium tuberculosis and non-tuberculosis bacteria |
| abstract | The present invention targets a gene (rpoB) encoding an RNA polymerase β subunit to detect and detect a mycobacterium tuberculosis complex and a mycobacteria other than Tubercle bacilli (MOTT). A primer pair for a duplex-polymerase chain reaction (duplex-PCR), and a method for differentially detecting and detecting tuberculosis bacteria and MOTT using the same, as well as a method for diagnosing tuberculosis and MOTT infection. In the present invention, using a rpoB gene as a target DNA, a dual PCR primer pair has been developed that can easily and effectively detect tuberculosis bacteria and MOTT. By simultaneously performing PCR using the two specific primer pairs, tubercle bacillus or MOTT rpoB DNA is amplified into single bands of different sizes according to the type of template DNA present in the sample, thereby infecting them according to their size. It could be confirmed. Therefore, according to the double PCR method using the primer pair of the present invention, only one copy of the rpoB gene, which is very well conserved while being present in a single copy in all mycobacteria, is simpler and more specific than any conventional method. It is possible to differentially detect tuberculosis bacteria and MOTT. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101291669-B1 |
| priorityDate | 1998-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 116.