| abstract |
The present invention relates to a triarylimidazole derivative represented by the following general formula (I), a pharmaceutically acceptable salt thereof, a preparation method thereof, and a cyclooxygenase-2 inhibitor containing an effective amount thereof. -2 inhibitor).n n n (I)n n n In the above formulan n n R 1 is a hydrogen group, 2-, 3-, 4- or 3,5-halogen group, 4-methyl group, or 3-fluoro-4-methoxy group,n n n R 2 is a methyl group,n n n R 3 is a hydrogen group, 4-halogen group, 4-methyl group, 4-benzyloxy group, 4-hydroxy group, 3,4-dimethoxy group, 3-methoxy-4-hydroxy group, 3- or 4-trifluoro Methyl, 3- (3,5-dichloro) phenoxy, 4-nitro or 4-phenoxy. |