http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100272623-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e82fc03c0fdcb1dadfc495c9ba125560 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-43504 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-815 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-165 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-20 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-81 |
| filingDate | 1998-07-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2000-11-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_550783c726107858242268ce39456948 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_68b58fb47840acf2eb5bf4a13ed10d42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_af29f769263a172488e63fe8b78200da |
| publicationDate | 2000-11-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-100272623-B1 |
| titleOfInvention | Mass Production Method of Elastase-Specific Inhibitory Peptides Derived from Korean Bloodsucker Leech Using Recombinant Yeast |
| abstract | The present invention uses glycerol as a carbon source to effectively produce a desired elastay-specific inhibitory protein, ie, Guamarin, from recombinant Pichia pastoris until the cell mass is suitable for expression and secretion. Obtaining a protein by quantitatively increasing the cells, stopping the supply of the carbon source for a period of time from a sharp increase in the amount of dissolved oxygen, depleting the carbon source, and incubating the oil with the addition of methanol, thereby obtaining hydrophobic interaction chromatography. Purification by chromatography and reversed phase chromatography to selectively inhibit the activity of elastase, which causes emphysema, chronic bronchitis, and adult respiratory distress syndrome, using recombinant yeast to overcome inactivation by free radicals Derived from Korean leeches LA's stay relates to a mass production method for inhibiting specific (elastase inhibitor) peptide. |
| priorityDate | 1998-07-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 76.