| abstract |
The present invention provides for the production of arthritis, cancer, tissue ulcers, restenosis, periodontal disease, bullous epidermal detachment, sclerosis, other diseases characterized by matrix metalloproteinase activity, AIDS, sepsis, septic shock and the production of TNF. A compound of formula (I) is useful for the treatment of a disease selected from the group consisting of other diseases, including:n n n Formula In n n n n n n n Wheren n n n, X, R 3 , R 4 and Ar are as defined in the specification. |