| abstract |
The present invention relates to a compound of formula (I) or a pharmaceutically acceptable salt thereof, which is an anti-inflammatory and allergy treatment.n n n n n n n n Wherein R 1 , R 2 and R 3 are independently hydrogen, halo, alkyl, alkoxy, phenoxy, phenyl, alkoxycarbonyl, -NR 13 R 14 , halogenated alkoxy, halogenated alkyl, benzyloxy, hydroxy, hydroxy Oxyalkyl, (C 2-6 alkoxycarbonyl) vinyl, -S (O) n R 7 , carbamoylalkyl, alkoxycarbonylalkyl, -CONR 11 R 12 or R 1 and R 2 together with phenyl ring naphthyl Group; R 4 and R 5 are independently hydrogen, alkyl or phenyl or R 4 and R 5 together with a carbon atom represent a C 3-6 cyclo alkyl group; R 6 is hydrogen, alkyl or ω-hydroxyalkyl, benzyl or phenyl; R 9 and R 10 are independently hydrogen, alkyl, halo, alkoxy, phenyl, hydroxyalkyl, alkoxycarbonyl, nitro, —NR 30 R 31 , alkanoyloxyalkyl or aminomethyl. Compositions containing these compounds and compositions containing them and methods of making them are also described. |