http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100235804-B1

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filingDate 1997-07-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 1999-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9d78d07778d0484557ff03f72e204db2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ff2208e29b4b0d9275ad1c9f57313543
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_77d1334155514c59be63776eb0c6d689
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cc02008a0a3529078b1b3dd4838c0591
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0d36f55c1f31b0133ef0289882c67c6d
publicationDate 1999-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber KR-100235804-B1
titleOfInvention 4-hydroxy-piperidine derivative
abstract The present invention relates to compounds of formula (I) and pharmaceutically acceptable acid addition salts thereof.n n n [Formula 1]n n n n n n n n Wherein, X is -0-, -NH-, -CH 2 -, -C0 2 -, -C0NH-, -C0N ( lower alkyl) -, -S- or -S0 2 -, and, R 1 to R 4 Are independently of each other hydrogen, halogen, hydroxy, amino, nitro, lower-accyl-sulfonylamido, 1- or 2-imidazolyl, 1- (1,2,4-triazolyl) or acetamido , R 5 and R 6 are independently of each other hydrogen, lower alkyl, hydroxy, lower alkoxy or oxo, and R 7 to R 10 are independently of each other hydrogen, lower alkyl, halogen, trifluoromethyl or lower-alkoxy, n is 0 or 1;n n n Compounds of the invention are NMDA (N-methyl-D-aspartate) -receptor subtype specific blockers.
priorityDate 1996-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID2904
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http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID21584252
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Total number of triples: 364.