| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_33c922e05f6133b7d72dbb849d77487d |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2740-16041
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-70578 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-86
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-28 |
| filingDate |
1997-02-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1999-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8bd871115062131e04fbdbf669682013
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5852d2e8d9bd9f09f120092e8977d486
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_30f408f7a80c311ad581509e441e7a24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fd844d04536a57a1a12de3e217e14fdb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1601ea68e5ced72e716870a681fefe76 |
| publicationDate |
1999-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
KR-100231318-B1 |
| titleOfInvention |
Retroviral vector having C-terminal part of tumor necrosis factor alpha receptor and method for inhibiting HIV-1 proliferation using same |
| abstract |
The present invention relates to a retroviral vector linking a C-terminal portion of a tumor necrosis factor-α (TNF-α) receptor (TNF R1) with a portion of LTR, a promoter of human immunodeficiency virus-1 (HIV-1), and the use thereof. To suppress the proliferation of HIV-1. The C-terminus of TNF R1 is located under the LTR deletion mutant strain (3s LTR) having only three recognition sites of the transcription factor Sp1 in the HIV-1 promoter (LTR). Expression of retroviral vectors linked to harmful genes encoding in HIV-1 infected cells can inhibit the proliferation of HIV-1 and can be used for the treatment of AIDS. |
| priorityDate |
1996-02-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |