| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bdad2480e9ab6e56c8d1dd65b648e333 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K36-185
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H13-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7024
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-70
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H13-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K36-23
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K36-185
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K36-00 |
| filingDate |
1997-03-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1999-11-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f764c332ac6c23abdf2db6e43e3adf5e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3613f1d03db8203676a9182d6098880f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0e6d234bcc1c22c70d7092b354da328b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9f11a92e42ed19f59b8fe8a668261bd1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6dfaa1d19094cd4e566cbe1d0bfe885e |
| publicationDate |
1999-11-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
KR-100228873-B1 |
| titleOfInvention |
Hepatocellular and anti-hepatic fibrosis therapy containing water-soluble extracts of Asiaticoside and Matecasoside isolated from Centella asiatica |
| abstract |
The present invention relates to a water-soluble extract of asiaticoside and matecasoside excellent in hepatocyte protection and antifibrotic effect from Centella asiatica (L) Urb, and a method for separating the same.n n n Methylene chloride was added to the extract obtained by adding ethanol aqueous solution to the sample, and the layers were separated. The supernatant was extracted with normal butane, and the normal butane layer was washed with caustic soda and washed with water. The butanol layer was concentrated under pressure, crystallized by adding ethyl acetate, separated, washed, and dried to separate an extract mixed with asiaticoside and matecasoside.n n n Soluble extracts were tested for toxic block and recovery effects by inducing toxicity to hepatocytes in rats. In order to confirm the anti-fibrotic effect, it was confirmed that the biliary ligation method and the liver fibrosis test had an effect of relieving fibrosis. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100530278-B1 |
| priorityDate |
1997-03-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |