http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100224370-B1

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filingDate 1996-07-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 1999-10-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_44bb0fbd7b11d045aad4cb4508e8c1b6
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publicationDate 1999-10-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber KR-100224370-B1
titleOfInvention Nifecotinyl-2-pyrrolidinone, preparation method thereof and anticonvulsant using the same
abstract The present invention relates to nifecotyl-2-pyrrolidinone represented by the following general formula (1), a pharmaceutically acceptable salt thereof, and an anticonvulsant having the same as an active ingredient.n n n n n n n n The substance according to the present invention is transformed into an amide by combining γ-aminobutyl acid (GABA), an amino acid-based compound, and nipecotic acid, which is one of the γ-aminobutyl acid intake inhibitors, Increases fat solubility than the original substance, facilitating the passage of BBB, and after being absorbed, it is degraded by in vivo yeast and acts as a γ-aminobutyl acid (GABA) and γ-aminobutyl acid intake inhibitor. Possible, ie two active substances, the application shows a very wide range of anticonvulsive activity.
priorityDate 1996-07-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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