http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100202279-B1

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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-34
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-22
filingDate 1997-05-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 1999-06-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fd0174a25a0ec898653663286b3b6537
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ee2a862607819ca60dc76f41f8209e29
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_599084b7258b18b06cd5a9229651d5f1
publicationDate 1999-06-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber KR-100202279-B1
titleOfInvention Process for preparing cefuroxime ester derivative
abstract The present invention is directed to an improved process for preparing the cefuroxime ester derivatives. The present invention maximizes the yield in crystallization of the product by reacting the starting material under neutral conditions without using a base in the preparation of cefuroxime 1-acetoxy ethyl ester, and the R: S isomer ratio is about 1: 1. In order to obtain, a solvent system of isopropanol and normal hexane may be used. The solvent-based mixing ratio is 1: 2, and after primary crystallization with isopropanol, crystallization is completed with normal hexane. The advantage of the present invention is that it is simpler than the conventional method, and it is possible to obtain a product of high purity and high yield.
priorityDate 1997-05-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 31.