abstract |
Reacting 3, 4, 6-trichloro-N-substituted phthalimide with potassium hydride in the absence of a catalyst at a temperature of 200-270 ° C. to form the corresponding trifluoro-N-substituted phthalimide, Hydrolysis of this in turn results in the formation of 3, 4, 6-trifluorophthalic acid to produce 3, 4, 6-trifluorogophthalic acid in high yield. |