http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100186656-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5198a2a21392d6cbc0bb4898b3fb3d29 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-745 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-745 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-36 |
| filingDate | 1994-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1999-04-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_76a2793a3e4ae472471182a756a5d02b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fe9ee31d69f3f8e2f096dfa2d175e4e6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4c939e38c044f22a888393a1d2eaeffc |
| publicationDate | 1999-04-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-100186656-B1 |
| titleOfInvention | Novel peptides and platelet aggregation inhibitors using electric peptides, blood coagulation inhibitors of circulating blood, cell adhesion inhibitors, tumor metastasis inhibitors, protection of platelet preparations for transfusion, platelet preparations for transfusion and platelet preparations |
| abstract | The present invention provides a peptide represented by the following general formula (I) or a salt thereof:n n n Rro-Ser-A-B-Asp-C-D (I)n n n In the above, A is one amino acid that does not have a guanidino group in the side chain, B is one amino acid, C is one amino acid having a hydrophobic group in the side chain, D is a hydroxyl group or an amino group .n n n The peptides of the present invention or salts thereof are useful because they exhibit excellent platelet aggregation inhibitory activity and blood coagulation inhibitory activity and are very safe for adulthood.n n n In addition, the present invention provides the following drugs containing the electric peptide or a salt thereof as an active ingredient: platelet aggregation inhibitors; Blood coagulation inhibitors; Tumor metastasis inhibitors; And protective agents for platelet preparations. In addition, the present invention provides a pharmaceutical formulation comprising an electrical peptide or a salt thereof, and a pharmaceutically acceptable carrier; A method of inhibiting platelet aggregation, comprising administering to a patient an effective amount of a pharmaceutically acceptable carrier and an electrical peptide or salt thereof; A method of inhibiting coagulation of blood circulating in vitro, comprising administering to the patient an effective amount of an electrical peptide or salt thereof together with a pharmaceutically acceptable carrier; A method of inhibiting cell adhesion, comprising administering to a patient an effective amount of an electrical peptide or salt thereof together with a pharmaceutically acceptable carrier; A method of inhibiting tumor metastasis, comprising administering to a patient an effective amount of an electrical peptide or salt thereof together with a pharmaceutically acceptable carrier; And adding an effective amount of the electrical peptide or salt thereof to the platelet preparation. |
| priorityDate | 1993-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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