http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-0184773-B1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_33c922e05f6133b7d72dbb849d77487d |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-27 |
filingDate | 1996-04-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 1999-04-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6cf290d6d69b4d3d5e918fc25533cc27 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_445e15d52514b3d51a2fcfa8594dee58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a74c44c348eabaf3f0e42cefbf09fd20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8999484d867c1a082e4c498cb788e53c |
publicationDate | 1999-04-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-0184773-B1 |
titleOfInvention | Method of Making Recombinant Human Factor VIII |
abstract | The present invention relates to a mass production method of recombinant human factor VIII having blood coagulation activity, wherein the 5'-end secretion signal sequence of the nucleotide sequence of the human factor VIII gene is randomly modified without changing the amino acid sequence. After obtaining a nucleotide sequence that minimizes the secondary structure of, the recombinant human factor VIII gene is inserted into a mammalian expression vector, and the recombinant human factor VIII is expressed by culturing mammalian cells transformed with the expression vector. Can be mass produced. |
priorityDate | 1996-04-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 265.