| abstract |
A novel pyrido [3,4-b] pyrazine-2,3 (1H, 4H) dione and its derivatives are aminothiazole-based cefe compounds with quaternary ammonium salts at the 3-position of cefem, and are Gram-positive and negative bacteria, Pseudomonas strains. The present invention relates to a novel cefem compound having a broader antimicrobial activity than existing drugs (CTX, CAZ) and a far superior AUC and half-life in terms of pharmacokinetics. |