| abstract |
The present invention encompasses long-term, continuous administration of organic nitrite to a patient in a dosage form capable of delivering a pharmaceutically sufficient amount of nitrite to the bloodstream of the patient (including the diseased animal), thereby providing at least 24 hours in the patient. A novel treatment method is provided for treating patients suffering from symptoms in need of effective vasodilator therapy without developing resistance.n n n The methods of the invention are also useful for treating symptoms such as angina, especially chronic stable angina, ischemia, congestive heart failure, and controlled hypertension and / or impotence in men. |