| abstract |
Purine or pyrimidine derivatives represented by the formula and pharmacologically acceptable salts thereofn n n n n n n n Wherein B is a purine or pyrimidine base selected from xanthine, substituted xanthine, guanine, substituted guanine, purine, substituted purine, cytosine, substituted cytosine, thymine, uracil, substituted uracil, adenine and substituted adenine; X and X 'Is the same or different and is a hydrogen, a cation of 1 to 6 carbon atoms or a salt-producing base; R' is independently hydrogen, 1 to 6 carbon atoms, 1 to 6 hydroxyalkyl or carbon atoms 2 To 7 alkanoyl; R is independently hydrogen, 1 to 6 carbon atoms, 1 to 6 hydroxyalkyl carbon atoms, 2 to 7 alkanoyl carbon atoms, or R is X when hydroxymethyl Or together with 'to form a -CH 2 -group, or R' together with R optionally form a group represented by the following formula;n n n n n n n n Wherein the dotted line is an arbitrary bond and Y and Z are the same or different and an azido, amino, hydroxy or halogen substituted C1-6 alkyl group; If Z is H or OH and any bond is absent, X 'and Y are optionally bonded to each other) |