http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-0165736-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1532cae5cef0d7b37d22500263519417 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y102-01024 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0008 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-165 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-36 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-02 |
| filingDate | 1995-03-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1999-01-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d652d4a09ac253eab9ae42a5e285744a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f1dcc9345989653d7711bcb8fecd7c85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_094116713adb4dc6995f80f0208d3d7e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_df9a8da97e6fd12f7757621e6a4fffa9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_81f54c5efe63f941edd77b470bd93d05 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b162462eefb3d27503a08d31286aa2c8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_820004a1e9ef2a6d394b0a2ccd079950 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ceea2116cc70244c24ebbeb50b4fa817 |
| publicationDate | 1999-01-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-0165736-B1 |
| titleOfInvention | Novel succinic semialdehyde dehydrogenase and preparation method thereof |
| abstract | The present invention relates to a novel succinic semialdehyde dehydrogenase (EC 1.2.1.24.) Isolated from bovine brain and a method for producing the same. The succinic semialdehyde dehydrogenase of the present invention is a dimer of about 110 kDa composed of two monomers each having a molecular weight of about 54 kDa, and has a very high substrate specificity for succinic semialdehyde, and an optimum pH of enzymatic activity is 9.0. Cysteine, lysine and arginine are involved in the activity. In addition, the succinic semialdehyde dehydrogenase of the present invention is treated with dapsone as an antiepileptic agent, diphenylhydantoin as an anticonvulsant and diazapam, and imipramine as an antidepressant / anti-anxiety agent. Activity is greatly inhibited. Accordingly, SSDH of the present invention may be applied to the development of inhibitors and activators of SSDH, and may be helpful in the treatment of various abnormalities caused by excessive accumulation of GHB and diseases caused when the body's level of GABA is abnormally low. |
| priorityDate | 1995-03-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 96.