http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-0162856-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2f953e662f0f4a6aedb6f11302833d60 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5014 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-48 |
| filingDate | 1994-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1999-05-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f47a88108c69ee4e086f7d51b0545f13 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d5ddee8289f3e9152fb921151a28c138 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_296796540af299526b6c8c4724ca1279 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c1711a56d9f10afc8d31daf2d50b9693 |
| publicationDate | 1999-05-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-0162856-B1 |
| titleOfInvention | Cytotoxicity screening method of S-alkylating agent and cytotoxic inhibitor of S-alkylating agent |
| abstract | Methods for screening cytotoxicity of S-alkylating agents and the use of dihydroxyisoquinoline as cytotoxic inhibitors of S-alkylating agents are provided. The cytotoxicity detection method of the S-alkylating agent of the present invention has the advantage of increasing the sensitivity of the detection method by using lymphocytes of the spleen as target cells, making the preparation of target cells simple, and reducing the search time. . In addition, dihydroxyisoquinoline, which is found to have a cytotoxic inhibitory effect of the S-alkylating agent according to the present invention, exhibits a cytotoxic inhibitory effect on the S-alkylating agent which is excellent even at a much lower concentration than the conventional inhibitor nicotinamide. |
| priorityDate | 1994-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 29.