| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fcd96347d65d8457bb9391f4f8ee3d2a |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-33
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D215-56
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C59-245 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-56
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-495
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-33
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C59-245 |
| filingDate |
1992-01-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1998-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e0751f0cc9f84dfd7f913f9c092136e4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_41da36fad3bf453426fcb95bdc9ee0fd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7b5e4b954fd660c32d5c7623e83969c5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ba3e421334e8bd149e8474a622fcd5d2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5674200adf2ac8dde4d33770afe34830 |
| publicationDate |
1998-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
KR-0159540-B1 |
| titleOfInvention |
Salts of quinolone-carboxylic acids and compositions thereof |
| abstract |
The present invention relates to an organic acid salt of quinolone-carboxylic acid of formula (I), a preparation method thereof, and a pharmaceutical composition containing the salt thereof.n n n n n n n n In which R represents cyclopropyl.n n n The compound of formula (I) is a known compound having a strong antimicrobial effect and is widely used in the treatment of infectious diseases, but is difficult to be used as an injection because it is poorly soluble in water. Several organic acids are known for this compound, with lactic acid being representative.n n n The solution of the present invention is an aqueous solution of the compound of formula (I) with 5-oxotetrahydrofuran-2-carboxylic acid instead of lactic acid as a solubilizer to significantly increase the solubility.n n n This invention makes the salt of 5-oxotetrahydrofuran-2-carboxylic acid of the said compound of formula (I), its manufacturing method, and the pharmaceutical composition containing the salt into the claim. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100840125-B1 |
| priorityDate |
1992-01-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |