http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-0151815-B1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_dd7c27b9ec61781656e6f039702fd568 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-545 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-30 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-96 |
filingDate | 1995-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 1998-10-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_028a5a96b3f8fb516130c3d61ea45cd3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7904a3667f669f112ab2344c24365e5b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d7106b86efe60f900336e733579feafc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dca8fea5141d9342feae1ea130a1fee2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_37aaed6c9ff51deaf96d5a068092c5a2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4b2be05c1a51a2f24a82179f9657064e |
publicationDate | 1998-10-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-0151815-B1 |
titleOfInvention | New preparation of antiviral 2,4-pyrimidinedione derivatives |
abstract | The present invention comprises the following general reaction comprising reacting a compound of formula (IV) with hexamethyldisilazane to obtain a compound of formula (II), which is reacted with a compound of formula (III) A novel process for the preparation of 2,4-pyrimidinedione derivatives of formula (I) and a process for the preparation of novel intermediate (IV) used therein, wherein the compound of formula (I) is an antiviral agent, in particular acquired immunodeficiency syndrome. (AIDS) Useful as a therapeutic.n n n n n n n n Wherein R 1 is a hydrogen atom; A methyl group unsubstituted or substituted with a C 1 -C 10 carbonyloxy group, a hydroxyl group, an azido group, a cyano group, a fluorine, a vinyl group, an amino group, a nitro group, a phenyl group, a C 1 -C 10 alkoxy group or a benzyloxy group; A cycloalkyl group of C 2 -C 10 ; A halogen atom, C 1 -C 5 alkyl, C 1 -C 5 alkoxy group, an amino group, a nitro group, a cyano group or a hydroxy group optionally substituted by a phenyl group of; Or a C 3 -C 10 heteroaryl group, R 2 is a hydrogen atom, a halogen atom, a methyl group, an ethyl group, an isopropyl group, a cyclopropyl group, a vinyl group, a vinyl group substituted with a halogen, an alkoxy of C 1 -C 8 groups, represents an allyl group or a benzyl, R 3 and R 4 are each independently a hydrogen atom, a halogen atom, C 1 -C 5 alkyl, C 1 -C 5 alkoxy group, an amino group, a nitro group, a cyano group, C An alkoxycarbonyl group of 2 -C 8 or a carbamoyl group of C 1 -C 8 , Z represents a sulfur atom or a methylene group, X represents a halogen atom or a sulfonyloxy group. |
priorityDate | 1994-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 106.