abstract |
The present invention relates to a method for producing an aromatic heterocyclic amine N-oxide, and more particularly, to an aromatic heterocyclic amine represented by the following structural formula (II) under a hydrogen fluoride (HF) aqueous catalyst, a dimethylformamide and methanol mixed solvent. The present invention relates to a novel process for producing an aromatic heterocyclic amine N-oxide represented by the following structural formula (I) by reacting with an m-chloroperbenzoic acid oxidizing agent in a high yield in a short time.n n n n n n n n In the above formula,n n n X and Y are the same or different and are CH or N, R is chloro, carboxylic acid, amino, oxo, C 1 to C 4 alkyl or ribose, n is the number of substituents R 1 to 3 Is an integer. |