http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-0134069-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5128cfc84a0fb189fceb3cd240c44493 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D277-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D277-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-425 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-64 |
| filingDate | 1994-01-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1998-04-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7df5ed17b7d7b448cebea11155966b0c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c3484049fc4029dcb9bd3dbfa9e628a0 |
| publicationDate | 1998-04-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-0134069-B1 |
| titleOfInvention | Benzothiazole sulfonamide derivatives, preparation thereof and uses thereof |
| abstract | Based on benzothiazole sulfonamido derivatives having protein kinase inhibitory activity such as protein kinase C and myosin light chain kinase, acid addition salts thereof, preparation method thereof, pharmaceutical compositions containing them and protein kinase inhibitors having these as active ingredients It is to provide a therapeutic or preventive agent for asthma.n n n The present invention is formula (1)n n n n n n n n (Wherein A is a lower alkylene group, R 1 is a hydrogen atom or a lower alkyl group, R 2 and R 3 are each independently a hydrogen atom or a lower alkyl group, or together a lower alkylene group, R 4 is a hydrogen atom, a lower alkyl group, an amino group) Benzothiazole sulfonamide derivatives represented by a dino group or a substituted phenyl group (which represents a lower alkyl group substituted with 1 to 2 hydrogen atoms, lower alkyl groups, lower alkoxy groups or halogen atoms, or methylenedioxy groups), and pharmaceuticals thereof It is an asthma treatment or prevention agent based on acceptable acid addition salt, the manufacturing method thereof, the pharmaceutical composition containing them, and the protein phosphatase inhibitory activity which uses them.n n n Compound (1) of the present invention and acid addition salts thereof and pharmaceutical compositions thereof have useful protein kinase inhibitory activities such as protein kinase C and myosin light chain kinase, and are useful as therapeutic agents or prophylactic agents for asthma based on protein kinase inhibitory action. |
| priorityDate | 1993-02-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 217.