http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-0123537-B1

Outgoing Links

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2e07369775d614939972ee78a4b7bf0c
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-00
filingDate 1993-04-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 1997-11-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4fee8a9f3c79a478dc7316cd2bb9ec48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_22a9e0564d51ce85a3700af010a52613
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_df3f161b42205e58255a7fa08463632a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_593564f7d8e27bedaa955dfab5605a21
publicationDate 1997-11-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber KR-0123537-B1
titleOfInvention Novel thorax virus strain, production method of thorax virus antigen, vaccine and pandemic hemorrhagic fever diagnostic reagent using the antigen
abstract The present application discloses a method for producing a Howang virus antigen, a novel virus of epidemic hemorrhagic fever, and a pandemic hemorrhagic vaccine and a diagnostic agent containing an antigen obtained by the method. More specifically, the crowbar virus is cultured in the brain cells of the mouse, the brain of the mouse is extracted, a large amount of the virus is extracted with a mixer and a sonicator, and then protamine sulfate, ethanol and an ultrafast centrifuge are used. Pure virus in the supernatant was isolated and formaldehyde solution was added to the viral antigen to inactivate the virus to purify the viral antigen obtained, or cultured in the Vero E6 cells, and then cultured and infected cells Was treated with a sonicator to extract the virus in the cell, and then obtained a pure virus using an ultrafast centrifuge, and then purified by the inactivation solution was added to the inactivated royal virus antigen and the inactivating agent to the virus antigen obtained Vaccine obtained by addition of, virus antigen obtained from above It discloses a new diagnosis of epidemic hemorrhagic fever containing the effective amount required for the antigen-antibody reaction.
priorityDate 1993-04-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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