abstract |
The present invention is a compound having a 4-amino-3-oximepyrrolidine-based substituent at position 7 of the quinolone mother nucleus, and has a novel quinoline (or naphthyridine) carbide of formula (I) having excellent antibacterial action and broad antibacterial spectrum. Acid derivatives, pharmaceutically acceptable salts thereof, and methods for preparing the same.n n n n n n n n Wherein Q is CH, CF, C-C1, C-OH, CO-methyl, or N, R is hydrogen, methyl, or amino, R 1 is cyclopropyl, ethyl, phenyl substituted with one or more fluorine atoms And R 2 represents hydrogen, C 1-4 straight or branched alkyl, phenyl or allyl. |