| abstract |
PROBLEM TO BE SOLVED: To combine a ligand, a spacer and a peptide linker useful for an in-vivo diagnostic agent and an internal radiotherapy using an anti-human MUC1 antibody Fab fragment whose binding activity is not attenuated by labeling with a metal, a fluorescent dye or the like. Body provision. SOLUTION: A complex composed of a biomolecule containing 3arm DOTA, a specific spacer, a specific peptide linker and an anti-human MUC1 antibody Fab fragment is not attenuated in binding activity by labeling with a metal, a fluorescent dye or the like, and has a diagnostic composition. It can be used as a product and / or a pharmaceutical composition. [Selection diagram] None |